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CHIP can remodel mature AhR complexes and mediate ubiquitination of both the AhR and the hsp90 in vitro.
The regulation of the aryl hydrocarbon receptor (AhR) protein levels has been an area of keen interest, given its important role in mediating the cellular adaptation and toxic response to several environmental pollutants. The carboxyl terminus of hsc70- interacting protein (CHIP) ubiquitin ligase wa...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527729/ https://ncbi.nlm.nih.gov/pubmed/17209571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062165b |
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