The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90

The aryl hydrocarbon receptor is a member of the nuclear receptor superfamily that associates with the molecular chaperone HSP90 in the cytoplasm. The activation mechanism of the AhR is not yet fully understood. It has been proposed that after binding of ligands such as 2,3,7,8-tetrachlorodibenzo-p-...

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Detalhes bibliográficos
Main Authors: Tsuji, Noriko, Fukuda, Kana, Nagata, Yuhtaroh, Okada, Hirotaka, Haga, Asami, Hatakeyama, Shiori, Yoshida, Shiho, Okamoto, Tomoya, Hosaka, Miki, Sekine, Kazuhiro, Ohtaka, Kei, Yamamoto, Soh, Otaka, Michiro, Grave, Ewa, Itoh, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-Blackwell 2014
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208086/
https://ncbi.nlm.nih.gov/pubmed/25349783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.09.003
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