HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells

Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic. Studies from our lab and others have reported that magnetic resonance spectroscopy (MRS)-detectable phosphocholine (PC) is elevated following SAHA treatment, providing a potential noninvasive biomark...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ward, Christopher S., Eriksson, Pia, Izquierdo-Garcia, Jose L., Brandes, Alissa H., Ronen, Sabrina M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633900/
https://ncbi.nlm.nih.gov/pubmed/23626839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062610
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