HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells

Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic. Studies from our lab and others have reported that magnetic resonance spectroscopy (MRS)-detectable phosphocholine (PC) is elevated following SAHA treatment, providing a potential noninvasive biomark...

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Detalhes bibliográficos
Main Authors: Ward, Christopher S., Eriksson, Pia, Izquierdo-Garcia, Jose L., Brandes, Alissa H., Ronen, Sabrina M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633900/
https://ncbi.nlm.nih.gov/pubmed/23626839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062610
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