HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells

Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic. Studies from our lab and others have reported that magnetic resonance spectroscopy (MRS)-detectable phosphocholine (PC) is elevated following SAHA treatment, providing a potential noninvasive biomark...

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Main Authors: Ward, Christopher S., Eriksson, Pia, Izquierdo-Garcia, Jose L., Brandes, Alissa H., Ronen, Sabrina M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633900/
https://ncbi.nlm.nih.gov/pubmed/23626839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062610
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