Prox1 Directly Interacts with LSD1 and Recruits the LSD1/NuRD Complex to Epigenetically Co-Repress CYP7A1 Transcription

Cholesterol 7α-hydroxylase (CYP7A1) catalyzes the first and rate-limiting step in the classical pathway of bile acids synthesis in liver and is crucial for maintaining lipid homeostasis. Hepatocyte nuclear factor 4α (HNF4α) and α(1)-fetoprotein transcription factor (FTF) are two major transcription...

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Detaylı Bibliyografya
Asıl Yazarlar: Ouyang, Huafang, Qin, Yi, Liu, Yanfeng, Xie, Youhua, Liu, Jing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633876/
https://ncbi.nlm.nih.gov/pubmed/23626788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062192
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