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Reduced Expression of miR-200 Family Members Contributes to Antiestrogen Resistance in LY2 Human Breast Cancer Cells

INTRODUCTION: The role of miRNAs in acquired endocrine-resistant breast cancer is not fully understood. One hallmark of tumor progression is epithelial-to-mesenchymal transition (EMT), characterized by a loss of cell adhesion resulting from reduced E-cadherin and increased cell mobility. miR-200 fam...

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Autori principali: Manavalan, Tissa T., Teng, Yun, Litchfield, Lacey M., Muluhngwi, Penn, Al-Rayyan, Numan, Klinge, Carolyn M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633860/
https://ncbi.nlm.nih.gov/pubmed/23626803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062334
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