5-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines

COUP-TFII is reduced in endocrine-resistant breast cancer cells and is negatively associated with tumor grade. Transient re-expression of COUP-TFII restores antiestrogen sensitivity in resistant LCC2 and LCC9 cells and repression of COUP-TFII results in antiestrogen-resistance in MCF-7 endocrine-sen...

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Detalhes bibliográficos
Main Authors: Al-Rayyan, Numan, Litchfield, Lacey M., Ivanova, Margarita M., Radde, Brandie N., Cheng, Alan, Elbedewy, Ahmed, Klinge, Carolyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021391/
https://ncbi.nlm.nih.gov/pubmed/24513177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.02.001
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