Estradiol Represses the G(D3) Synthase Gene ST8SIA1 Expression in Human Breast Cancer Cells by Preventing NFκB Binding to ST8SIA1 Promoter

Recent data have underlined a possible role of G(D3) synthase (GD3S) and complex gangliosides in Estrogen Receptor (ER) negative breast cancer progression. Here, we describe the main transcript of the GD3S coding gene ST8SIA1 expressed in breast tumors. We characterized the corresponding core promot...

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Detalhes bibliográficos
Main Authors: Bobowski, Marie, Vincent, Audrey, Steenackers, Agata, Colomb, Florent, Van Seuningen, Isabelle, Julien, Sylvain, Delannoy, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633854/
https://ncbi.nlm.nih.gov/pubmed/23626833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062559
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