Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes

BACKGROUND: The animal sialyltransferases, which catalyze the transfer of sialic acid to the glycan moiety of glycoconjugates, are subdivided into four families: ST3Gal, ST6Gal, ST6GalNAc and ST8Sia, based on acceptor sugar specificity and glycosidic linkage formed. Despite low overall sequence iden...

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Détails bibliographiques
Auteurs principaux: Harduin-Lepers, Anne, Petit, Daniel, Mollicone, Rosella, Delannoy, Philippe, Petit, Jean-Michel, Oriol, Rafael
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564942/
https://ncbi.nlm.nih.gov/pubmed/18811928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-258
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