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AKT Inhibition Mitigates GRP78 (Glucose-regulated Protein) Expression and Contribution to Chemoresistance in Endometrial Cancers
Overexpression of the unfolded protein response (UPR) master regulator GRP78 is associated with poor prognosis and therapeutic resistance in numerous human cancers, yet its role in endometrial cancers (EC) is undefined. To better understand the contribution of GRP78 to EC, we examined its expression...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633665/ https://ncbi.nlm.nih.gov/pubmed/23280503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27994 |
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