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KLF4 and SOX9 Transcription Factors Antagonize β-Catenin and Inhibit TCF-Activity In Cancer Cells
The transcriptional activator β-catenin is a key mediator of the canonical Wnt signaling pathway. β-catenin itself does not bind DNA but functions via interaction with T-cell factor (TCF)/ lymphoid-enhancing factor (LEF) transcription factors. Thus, in the case of active Wnt signaling, β-catenin, in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633466/ https://ncbi.nlm.nih.gov/pubmed/22766303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.06.027 |
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