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KLF4 Interacts with β-Catenin/TCF4 and Blocks p300/CBP Recruitment by β-Catenin

Wnt signaling is crucial in the organization and maintenance of the human intestinal epithelium, and somatic mutations that result in deregulated Wnt signaling are an early event in the development of colorectal cancer. The Wnt ligand ultimately results in the stabilization of cytoplasmic β-catenin,...

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Detalhes bibliográficos
Main Authors: Evans, Paul M., Chen, Xi, Zhang, Wen, Liu, Chunming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798472/
https://ncbi.nlm.nih.gov/pubmed/19901072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00063-09
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