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KLF4 Interacts with β-Catenin/TCF4 and Blocks p300/CBP Recruitment by β-Catenin

Wnt signaling is crucial in the organization and maintenance of the human intestinal epithelium, and somatic mutations that result in deregulated Wnt signaling are an early event in the development of colorectal cancer. The Wnt ligand ultimately results in the stabilization of cytoplasmic β-catenin,...

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Hlavní autoři: Evans, Paul M., Chen, Xi, Zhang, Wen, Liu, Chunming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798472/
https://ncbi.nlm.nih.gov/pubmed/19901072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00063-09
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