Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure

Immunization with a recombinant yeast-expressed Plasmodium falciparum merozoite surface protein 3 (MSP3) protected Aotus nancymai monkeys against a virulent challenge infection. Unfortunately, the production process for this yeast-expressed material was not optimal for human trials. In an effort to...

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Hauptverfasser: Tsai, Chiawei W., Duggan, Peter F., Jin, Albert J., MacDonald, Nicholas J., Kotova, Svetlana, Lebowitz, Jacob, Hurt, Darrell E., Shimp, Richard L., Lambert, Lynn, Miller, Louis H., Long, Carole A., Saul, Allan, Narum, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633458/
https://ncbi.nlm.nih.gov/pubmed/19073223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2008.11.006
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