Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout

AIMS: We determined the role of the Rho kinase (ROCK) isoforms in diabetes-induced vascular endothelial dysfunction and enhancement of arginase activity and expression. METHODS AND RESULTS: Studies were performed in aortic tissues from haplo-insufficient (H-I) ROCK1 and ROCK2 mice and wild-type (WT)...

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Detalhes bibliográficos
Main Authors: Yao, Lin, Chandra, Surabhi, Toque, Haroldo A., Bhatta, Anil, Rojas, Modesto, Caldwell, Ruth B., Caldwell, R. William
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633399/
https://ncbi.nlm.nih.gov/pubmed/23250919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs371
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