Mutant p53 Attenuates the Anti-Tumorigenic Activity of Fibroblasts-Secreted Interferon Beta

Mutations in the p53 tumor suppressor protein are highly frequent in tumors and often endow cells with tumorigenic capacities. We sought to examine a possible role for mutant p53 in the cross-talk between cancer cells and their surrounding stroma, which is a crucial factor affecting tumor outcome. H...

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Detalhes bibliográficos
Main Authors: Madar, Shalom, Harel, Einav, Goldstein, Ido, Stein, Yan, Kogan-Sakin, Ira, Kamer, Iris, Solomon, Hilla, Dekel, Elya, Tal, Perry, Goldfinger, Naomi, Friedlander, Gilgi, Rotter, Varda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632588/
https://ncbi.nlm.nih.gov/pubmed/23630584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061353
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