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p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production

BACKGROUND: The p53 tumor suppressor protein is a transcription factor that initiates transcriptional programs aimed at inhibiting carcinogenesis. p53 represses metabolic pathways that support tumor development (such as glycolysis and the pentose phosphate pathway (PPP)) and enhances metabolic pathw...

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Bibliografiske detaljer
Main Authors: Goldstein, Ido, Yizhak, Keren, Madar, Shalom, Goldfinger, Naomi, Ruppin, Eytan, Rotter, Varda
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178212/
https://ncbi.nlm.nih.gov/pubmed/24280180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-9
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