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p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production

BACKGROUND: The p53 tumor suppressor protein is a transcription factor that initiates transcriptional programs aimed at inhibiting carcinogenesis. p53 represses metabolic pathways that support tumor development (such as glycolysis and the pentose phosphate pathway (PPP)) and enhances metabolic pathw...

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Detalhes bibliográficos
Main Authors: Goldstein, Ido, Yizhak, Keren, Madar, Shalom, Goldfinger, Naomi, Ruppin, Eytan, Rotter, Varda
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178212/
https://ncbi.nlm.nih.gov/pubmed/24280180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-9
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