Conditional Activation of β-Catenin Signaling Leads to Severe Defects in Intervertebral Disc Tissue

OBJECTIVE: The incidence of low back pain is extremely high and is often linked to intervertebral disc (IVD) degeneration. The mechanism of this disease is currently unknown. In this study, we have investigated the role of β-catenin signaling in IVD tissue function. METHODS: β-catenin protein levels...

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Detalhes bibliográficos
Main Authors: Wang, Meina, Tang, Dezhi, Shu, Bing, Wang, Baoli, Jin, Hongting, Hao, Suyang, Dresser, Karen A., Shen, Jie, Im, Hee-Jeong, Sampson, Erik R., Rubery, Paul T., Zuscik, Michael J., Schwarz, Edward M., O'Keefe, Regis J., Wang, Yongjun, Chen, Di
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632450/
https://ncbi.nlm.nih.gov/pubmed/22422036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34469
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