Genetic and Pharmacologic Disruption of Interleukin-1β Signaling Inhibits Experimental Aortic Aneurysm Formation

OBJECTIVE: Abdominal aortic aneurysms (AAAs) are common, but their exact pathogenesis remains unknown and no specific medical therapies are available. We sought to evaluate interleukin-1β (IL-1β) and interleukin-1 receptor (IL-1R) in an experimental AAA model to identify novel therapeutic targets fo...

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Detalhes bibliográficos
Main Authors: Johnston, William F., Salmon, Morgan, Su, Gang, Lu, Guanyi, Stone, Matthew L., Zhao, Yunge, Owens, Gary K., Upchurch, Gilbert R., Ailawadi, Gorav
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632435/
https://ncbi.nlm.nih.gov/pubmed/23288154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300432
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