Loading...

Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases.

The phosphorylation of the alpha-subunit of initiation factor eIF-2 leads to an inhibition of protein synthesis in mammalian cells. We have performed site-directed mutagenesis on a cDNA encoding the alpha-subunit of human eIF-2 and have replaced the candidate sites of phosphorylation, Ser-48 and Ser...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Pathak, V K, Schindler, D, Hershey, J W
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC363234/
https://ncbi.nlm.nih.gov/pubmed/3352609
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!