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Local modulation of cystic fibrosis conductance regulator: cytoskeleton and compartmentalized cAMP signalling
The cystic fibrosis conductance regulator (CFTR) is a cAMP-regulated Cl(−) channel expressed predominantly at the apical membrane of secreting epithelial cells. Mutations in the CFTR gene lead to cystic fibrosis, the most frequent genetic disease in the Caucasian population. The most common mutation...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632233/ https://ncbi.nlm.nih.gov/pubmed/23072488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12017 |
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