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WTX: An Unexpected Regulator for p53
The WTX gene is frequently lost or mutated in Wilms’ tumor. In this issue of Molecular Cell, Kim et al., identifies WTX modulation of the p53 tumor suppressor activity through regulating p53 acetylation. Therefore, WTX differentially regulates the oncogenic β-catenin pathway and the tumor suppressin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632215/ https://ncbi.nlm.nih.gov/pubmed/22405270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.02.010 |
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