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Modes of p53 Regulation
The traditional view of p53 activation includes three steps—p53 stabilization, DNA binding, and transcriptional activation. However, recent studies indicate that each step of p53 activation is more complex than originally anticipated. Moreover, both genetic studies in mice and in vitro studies with...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737742/ https://ncbi.nlm.nih.gov/pubmed/19450511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.04.050 |
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