Induction of Wilms’ tumor protein (WT1)-specific antitumor immunity using a truncated WT1-expressing adenovirus vaccine

PURPOSE: Wilms’ tumor protein (WT1) is overexpressed in most leukemias and many solid tumors, and is a promising target for tumor immunotherapy. WT1 peptide-based cancer vaccines have been reported but have limited application due to HLA-restriction of the peptides. We sought to vaccinate using aden...

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Detalhes bibliográficos
Main Authors: Osada, Takuya, Woo, Christopher Y., McKinney, Matthew, Yang, Xiao Yi, Lei, Gangjun, LaBreche, Heather G., Hartman, Zachary C, Niedzwiecki, Donna, Chao, Nelson, Amalfitano, Andrea, Morse, Michael A., Lyerly, H. Kim, Clay, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631522/
https://ncbi.nlm.nih.gov/pubmed/19351755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2589
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