Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis

BACKGROUND & AIMS: Dysregulated glucose homeostasis and lipid accumulation characterize non-alcoholic fatty liver disease (NAFLD), but underlying mechanisms are obscure. We report here that Krüppel-like factor 6 (KLF6), a ubiquitous transcription factor that promotes adipocyte differentiation, a...

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Main Authors: Bechmann, Lars P., Vetter, Diana, Ishida, Junichi, Hannivoort, Rebekka A., Lang, Ursula E., Kocabayoglu, Peri, Fiel, M. Isabel, Muñoz, Ursula, Patman, Gillian L., Ge, Fengxia, Yakar, Shoshana, Li, Xiaosong, Agius, Loranne, Lee, Young-Min, Zhang, Weijia, Hui, Kei Yiu, Televantou, Despina, Schwartz, Gary J., LeRoith, Derek, Berk, Paul D., Nagai, Ryozo, Suzuki, Toru, Reeves, Helen L., Friedman, Scott L.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631429/
https://ncbi.nlm.nih.gov/pubmed/23353867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.01.020
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