Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis

BACKGROUND & AIMS: Dysregulated glucose homeostasis and lipid accumulation characterize non-alcoholic fatty liver disease (NAFLD), but underlying mechanisms are obscure. We report here that Krüppel-like factor 6 (KLF6), a ubiquitous transcription factor that promotes adipocyte differentiation, a...

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Päätekijät: Bechmann, Lars P., Vetter, Diana, Ishida, Junichi, Hannivoort, Rebekka A., Lang, Ursula E., Kocabayoglu, Peri, Fiel, M. Isabel, Muñoz, Ursula, Patman, Gillian L., Ge, Fengxia, Yakar, Shoshana, Li, Xiaosong, Agius, Loranne, Lee, Young-Min, Zhang, Weijia, Hui, Kei Yiu, Televantou, Despina, Schwartz, Gary J., LeRoith, Derek, Berk, Paul D., Nagai, Ryozo, Suzuki, Toru, Reeves, Helen L., Friedman, Scott L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631429/
https://ncbi.nlm.nih.gov/pubmed/23353867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.01.020
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