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Conformational Control of the Ste5 Scaffold Protein Insulates Against MAP Kinase Misactivation()

Cells re-use signaling proteins in multiple pathways, raising the potential for improper crosstalk. Scaffold proteins are thought to insulate against such miscommunication by sequestering proteins into distinct physical complexes. We show that the scaffold protein Ste5, which organizes the yeast mat...

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Bibliografiska uppgifter
Huvudupphovsmän: Zalatan, Jesse G., Coyle, Scott M., Rajan, Saravanan, Sidhu, Sachdev S., Lim, Wendell A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631425/
https://ncbi.nlm.nih.gov/pubmed/22878499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1220683
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