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Scaffold-Assisted Catalysis: A Novel Domain In the Ste5 Scaffold Protein is Required to Unlock the MAPK Fus3 for Phosphorylation by the MAPKK Ste7

The scaffold protein Ste5 is required to properly direct signaling through the yeast mating pathway to the mitogen-activated protein kinase (MAPK), Fus3. Scaffolds are thought to function by tethering kinase and substrate in proximity. We find, however, that the previously identified Fus3-binding si...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Good, Matthew, Tang, Grace, Singleton, Julie, Remenyi, Attila, Lim, Wendell A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777755/
https://ncbi.nlm.nih.gov/pubmed/19303851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.049
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