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The tricky path to recombining X and Y chromosomes in meiosis
Sex chromosomes are the Achilles heel of male meiosis in mammals.(1) Mis-segregation of the X and Y chromosomes leads to sex chromosome aneuploidies, with clinical outcomes such as infertility and Klinefelter syndrome.(2) Successful meiotic divisions require that all chromosomes find their homologou...
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Κύριοι συγγραφείς: | , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2012
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631422/ https://ncbi.nlm.nih.gov/pubmed/22954211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06593.x |
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