Inherent sex-dependent regulation of human hepatic CYP3A5

BACKGROUND AND PURPOSE: Expression of hepatic cytochromes P450 (CYP) in all species examined, including humans, is generally sexually dimorphic. We examined the sex-dependent expression of CYP3A5 and the hormone-regulated molecular mechanism(s) responsible for any dimorphism. EXPERIMENTAL APPROACH:...

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Hlavní autoři: Thangavel, Chellappagounder, Boopathi, Ettickan, Shapiro, Bernard H
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631386/
https://ncbi.nlm.nih.gov/pubmed/22994453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02222.x
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