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The HER2- and Heregulin β1 (HRG)-inducible TNFR Superfamily Member Fn14 Promotes HRG-driven Cell Migration, Invasion and MMP9 Expression

Human epidermal growth factor receptor (HER)-2 overexpression occurs in 15–20% of all breast cancers and is associated with increased metastatic potential and poor patient survival. Abnormal HER2 activation, either through HER2 overexpression or heregulin (HRG):HER3 binding, elicits the formation of...

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Detalhes bibliográficos
Main Authors: Asrani, Kaushal, Keri, Ruth A., Galisteo, Rebeca, Brown, Sharron A. N., Morgan, Sarah J., Ghosh, Arundhati, Tran, Nhan L., Winkles, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631278/
https://ncbi.nlm.nih.gov/pubmed/23378579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-12-0542
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