Impact of Diffusion Barriers to Small Cytotoxic Molecules on the Efficacy of Immunotherapy in Breast Cancer

Molecular-focused cancer therapies, e.g., molecularly targeted therapy and immunotherapy, so far demonstrate only limited efficacy in cancer patients. We hypothesize that underestimating the role of biophysical factors that impact the delivery of drugs or cytotoxic cells to the target sites (for ass...

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Autori principali: Das, Hiranmoy, Wang, Zhihui, Niazi, M. Khalid Khan, Aggarwal, Reeva, Lu, Jingwei, Kanji, Suman, Das, Manjusri, Joseph, Matthew, Gurcan, Metin, Cristini, Vittorio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631240/
https://ncbi.nlm.nih.gov/pubmed/23620747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061398
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