Impact of Diffusion Barriers to Small Cytotoxic Molecules on the Efficacy of Immunotherapy in Breast Cancer

Molecular-focused cancer therapies, e.g., molecularly targeted therapy and immunotherapy, so far demonstrate only limited efficacy in cancer patients. We hypothesize that underestimating the role of biophysical factors that impact the delivery of drugs or cytotoxic cells to the target sites (for ass...

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Detalhes bibliográficos
Main Authors: Das, Hiranmoy, Wang, Zhihui, Niazi, M. Khalid Khan, Aggarwal, Reeva, Lu, Jingwei, Kanji, Suman, Das, Manjusri, Joseph, Matthew, Gurcan, Metin, Cristini, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631240/
https://ncbi.nlm.nih.gov/pubmed/23620747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061398
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