Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhance cytotoxicity of ovarian cancer cells

Many ovarian cancer cells express stress-related molecule MICA/B on their surface that is recognized by Vγ2Vδ2 T cells through their NKG2D receptor, which is transmitted to downstream stress-signaling pathway. However, it is yet to be established how Vγ2Vδ2 T cells-mediated recognition of MICA/B sig...

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Main Authors: Lu, Jingwei, Das, Manjusri, Kanji, Suman, Aggarwal, Reeva, Joseph, Matthew, Ray, Alo, Shapiro, Charles L., Pompili, Vincent J., Das, Hiranmoy
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082796/
https://ncbi.nlm.nih.gov/pubmed/24726882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.04.003
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