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Substrate Placement Influences Reactivity in Non-heme Fe(II) Halogenases and Hydroxylases
We employ error-corrected density functional theory methods to map out the dependence of reactivity on substrate position for SyrB2, a member of a family of non-heme iron halogenases and hydroxylases that are only reactive toward amino acid substrates delivered via prosthetic phosphopantetheine arms...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630895/ https://ncbi.nlm.nih.gov/pubmed/23449977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.415570 |
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