An Intracellular Domain Fragment of the p75 Neurotrophin Receptor (p75(NTR)) Enhances Tropomyosin Receptor Kinase A (TrkA) Receptor Function

Facilitation of nerve growth factor (NGF) signaling by the p75 neurotrophin receptor (p75(NTR)) is critical for neuronal survival and differentiation. However, the interaction between p75(NTR) and TrkA receptors required for this activity is not understood. Here, we report that a specific 29-amino a...

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Bibliographic Details
Main Authors: Matusica, Dusan, Skeldal, Sune, Sykes, Alex M., Palstra, Nickless, Sharma, Aanchal, Coulson, Elizabeth J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630867/
https://ncbi.nlm.nih.gov/pubmed/23471969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.436469
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