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In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

Macroautophagy mediates the bulk degradation of cytoplasmic components. It accounts for the degradation of most long-lived proteins: cytoplasmic constituents, including organelles, are sequestered into autophagosomes, which subsequently fuse with lysosomes, where degradation occurs. Although the pos...

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Autors principals: Mizushima, Noboru, Yamamoto, Akitsugu, Matsui, Makoto, Yoshimori, Tamotsu, Ohsumi, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC363084/
https://ncbi.nlm.nih.gov/pubmed/14699058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-09-0704
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