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Apg7p/Cvt2p: A Novel Protein-activating Enzyme Essential for Autophagy

In the yeast Saccharomyces cerevisiae, the Apg12p–Apg5p conjugating system is essential for autophagy. Apg7p is required for the conjugation reaction, because Apg12p is unable to form a conjugate with Apg5p in the apg7/cvt2 mutant. Apg7p shows a significant similarity to a ubiquitin-activating enzym...

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Bibliografische gegevens
Hoofdauteurs: Tanida, Isei, Mizushima, Noboru, Kiyooka, Miho, Ohsumi, Mariko, Ueno, Takashi, Ohsumi, Yoshinori, Kominami, Eiki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25280/
https://ncbi.nlm.nih.gov/pubmed/10233150
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