Apg7p/Cvt2p: A Novel Protein-activating Enzyme Essential for Autophagy

In the yeast Saccharomyces cerevisiae, the Apg12p–Apg5p conjugating system is essential for autophagy. Apg7p is required for the conjugation reaction, because Apg12p is unable to form a conjugate with Apg5p in the apg7/cvt2 mutant. Apg7p shows a significant similarity to a ubiquitin-activating enzym...

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izdano v:	Mol Biol Cell
Principais autores:	Tanida, Isei, Mizushima, Noboru, Kiyooka, Miho, Ohsumi, Mariko, Ueno, Takashi, Ohsumi, Yoshinori, Kominami, Eiki
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Cell Biology 1999
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25280/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10233150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.5.1367
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