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The Mouse SKD1, a Homologue of Yeast Vps4p, Is Required for Normal Endosomal Trafficking and Morphology in Mammalian Cells

The mouse SKD1 is an AAA-type ATPase homologous to the yeast Vps4p implicated in transport from endosomes to the vacuole. To elucidate a possible role of SKD1 in mammalian endocytosis, we generated a mutant SKD1, harboring a mutation (E235Q) that is equivalent to the dominant negative mutation (E233...

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Detalhes bibliográficos
Main Authors: Yoshimori, Tamotsu, Yamagata, Fumi, Yamamoto, Akitsugu, Mizushima, Noboru, Kabeya, Yukiko, Nara, Atsuki, Miwako, Ishido, Ohashi, Masato, Ohsumi, Mariko, Ohsumi, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14807/
https://ncbi.nlm.nih.gov/pubmed/10679028
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