Interaction with Smad4 Is Indispensable for Suppression of BMP Signaling by c-Ski

c-Ski is a transcriptional corepressor that interacts strongly with Smad2, Smad3, and Smad4 but only weakly with Smad1 and Smad5. Through binding to Smad proteins, c-Ski suppresses signaling of transforming growth factor-β (TGF-β) as well as bone morphogenetic proteins (BMPs). In the present study,...

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Autori principali: Takeda, Masafumi, Mizuide, Masafumi, Oka, Masako, Watabe, Tetsuro, Inoue, Hirofumi, Suzuki, Hiroyuki, Fujita, Toshiro, Imamura, Takeshi, Miyazono, Kohei, Miyazawa, Keiji
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC363053/
https://ncbi.nlm.nih.gov/pubmed/14699069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0478
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