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Functional Heterogeneity of Bone Morphogenetic Protein Receptor-II Mutants Found in Patients with Primary Pulmonary Hypertension

Germline mutations in the BMPR2 gene encoding bone morphogenetic protein (BMP) type II receptor (BMPR-II) have been reported in patients with primary pulmonary hypertension (PPH), but the contribution of various types of mutations found in PPH to the pathogenesis of clinical phenotypes has not been...

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Udgivet i:Mol Biol Cell
Principais autores: Nishihara, Ayako, Watabe, Tetsuro, Imamura, Takeshi, Miyazono, Kohei
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12221115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-02-0063
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