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Nutrient deprivation regulates DNA damage repair in cardiomyocytes via loss of the base-excision repair enzyme OGG1

Oxidative stress contributes to the pathogenesis of many diseases, including heart failure, but the role and regulation of oxidative DNA damage in many cases have not been studied. Here, we set out to examine how oxidative DNA damage is regulated in cardiomyocytes. Compared to normal healthy control...

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Bibliografiske detaljer
Main Authors: Siggens, Lee, Figg, Nichola, Bennett, Martin, Foo, Roger
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630495/
https://ncbi.nlm.nih.gov/pubmed/22302830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-197525
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