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Bio-Inspired Liposomal Thrombomodulin Conjugate through Bio-Orthogonal Chemistry
We report the synthesis of bio-inspired liposomal thrombomodulin (TM) conjugates by chemoselective and site-specific liposomal conjugation of recombinant TM at C-terminus. TM is an endothelial cell membrane protein that acts as a major cofactor in the protein C anticoagulant pathway. To closely mimi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630279/ https://ncbi.nlm.nih.gov/pubmed/23458546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300399f |
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