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Bio-Inspired Liposomal Thrombomodulin Conjugate through Bio-Orthogonal Chemistry

We report the synthesis of bio-inspired liposomal thrombomodulin (TM) conjugates by chemoselective and site-specific liposomal conjugation of recombinant TM at C-terminus. TM is an endothelial cell membrane protein that acts as a major cofactor in the protein C anticoagulant pathway. To closely mimi...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Hailong, Weingart, Jacob, Jiang, Rui, Peng, Jianhao, Wu, Qingyu, Sun, Xue-Long
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630279/
https://ncbi.nlm.nih.gov/pubmed/23458546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300399f
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