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CYP24A1 and CYP27B1 Polymorphisms Modulate Vitamin D Metabolism in Colon Cancer Cells

Vitamin D is a well-studied agent for cancer chemoprevention and treatment. Its chief circulating metabolite, 25-hydroxyvitamin D, is converted into the active hormone 1,25-dihydroxyvitamin D (1,25D) by the cytochrome P450 enzyme CYP27B1 in kidney and other tissues. 1,25D is then deactivated by CYP2...

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Detaylı Bibliyografya
Asıl Yazarlar: Jacobs, Elizabeth T., Van Pelt, Chad, Forster, Ryan E., Zaidi, Wasiq, Hibler, Elizabeth A., Galligan, Michael A., Haussler, Mark R., Jurutka, Peter W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630267/
https://ncbi.nlm.nih.gov/pubmed/23423976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4134
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