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Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence

Low circulating levels of vitamin D have been implicated in colorectal cancer risk. The biological actions of the hormonal form of vitamin D, 1,25(OH)(2)D(3), are mediated by the vitamin D receptor (VDR), which heterodimerizes with retinoid X receptors (RXRs). We applied a single nucleotide polymorp...

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Detalhes bibliográficos
Main Authors: Egan, Jan B., Thompson, Patricia A., Ashbeck, Erin L., Conti, David V., Duggan, David, Hibler, Elizabeth, Jurutka, Peter W., LeRoy, Elizabeth C., Martínez, María Elena, Mount, David, Jacobs, Elizabeth T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019606/
https://ncbi.nlm.nih.gov/pubmed/20145122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3264
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