Expression of raf oncogenes activates the PEA1 transcription factor motif.

PEA1 (AP1) motif transcription enhancer activity was stimulated by v-raf and more efficiently by activated c-raf-1 or A-raf than by their normal counterparts, in agreement with a role for PEA1 in transformation by raf. Mutations in the ATP-binding site of v-raf prevented activation, suggesting that...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Wasylyk, C, Wasylyk, B, Heidecker, G, Huleihel, M, Rapp, U R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2501665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.5.2247-2250.1989
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