Expression of raf oncogenes activates the PEA1 transcription factor motif.
PEA1 (AP1) motif transcription enhancer activity was stimulated by v-raf and more efficiently by activated c-raf-1 or A-raf than by their normal counterparts, in agreement with a role for PEA1 in transformation by raf. Mutations in the ATP-binding site of v-raf prevented activation, suggesting that...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
1989
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2501665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.5.2247-2250.1989 |
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