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Expression of raf oncogenes activates the PEA1 transcription factor motif.

PEA1 (AP1) motif transcription enhancer activity was stimulated by v-raf and more efficiently by activated c-raf-1 or A-raf than by their normal counterparts, in agreement with a role for PEA1 in transformation by raf. Mutations in the ATP-binding site of v-raf prevented activation, suggesting that...

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Detalhes bibliográficos
Main Authors: Wasylyk, C, Wasylyk, B, Heidecker, G, Huleihel, M, Rapp, U R
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC363023/
https://ncbi.nlm.nih.gov/pubmed/2501665
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